Hope your pup is doing better!! . I only researched it after he started not feeling well, just trusted my vet that this was safe. I won't be letting this go and I'll be actively pursuing recourse from the manufacturer and vet in any way I can. She does have history of seizures. Simparicaworks by impacting the nervous system of invertebrates such as fleas and ticks. Simparica, Nexgard, Bravecto and Credelio are part of a group called Isoxazoline drugs. Today shes been panting. 2-6 days in vomiting here and there. Strictly natural with zero side effects from now on. So sad as he was once a happy healthy dog with no prior health issues. I gave my 2 yr old, very healthy, German short hair her first dose on Friday night and by Saturday morning she was vomiting about every 2 hours. He is my first dog, he is 5yrs old now, and this is all new. He is 5 months old. Mine passed within 24 hours of the first dose. I gave this to my 2 rescue frenchies.. 2 days after 1 of them threw up..she didn't want to eat and started stumbling..leaning to the right, I thought vestibular but that is old dogs disease..I took her to the vet, did bloodwork that came back ok..she is on steroids and anti nausea meds..she is eating now..drinking alot and acts like she is deaf..she is only 6 yrs old. I gave him this medication last Thursday. Is it effective? Hello! Yesterday one baby threw up four times within one hour of taking her chewable. Company asked us to do diagnostic testing at vet. I hate that I did this to her and I hate that the Vet does not seem to care. I called my vet but because of Covid they are so behind in appts and would not see him until a month from then. I understand them charging for the Euthanasia and cremation but they said they would keep her for 12 hours and she was put down at around 3:00 which was 1/2 the time they agreed on.Now he will get none of the fees back that the company offered for the dogs care, and hey don't have their dog .On top of that they have 3,500.00 vet bills.Why are vets allowed to charge so much?it is more than a person.It really seems as though they don't care about the pets or the people that own them Also why is these types of flea meds still on the market and why is there no legal action available for the poor consumers.I feel like they were legally assaulted by all involved and let us not forget the poor 2 year old rescue dog who ended up having a terrible short life.How unfair. There is also a chance that hell need a surgery. Some adverse reactions to Simparica include tremors, decreased awareness of body movement, loss of control over bodily movements, problems blinking, and/or seizures. We rushed him to the emergency vet and they put him on keppra to stop the seizures. The diarrhea and vomiting went away after a few days but the cough has lingered for over a month now even with treatment. Anything with tick prevention is in the same class of drugs. supply) at Chewy.com. My best friend's new puppy has had diarrhea for 14 days after taking one dose of Simparica. She's finally resting at home, but still not able to walk, run, eat, etc. The Simparica was recommended by the vet. I gave them their 2nd dose, and 24 hours later, the Collie mix (Bella) was throwing up, lethargic, unsteady, drinking obsessively, panting, and could hardly walk. gave this to my dog three different times. That is the only thing that has changed in her routine. Heal quickly and clumps of hair fall out. Side effects The contra indication is important to know before you utilize the simparica. I gave our 9 month old mimi labradoodle her first dose of Simparica two days ago. Today June 1,2022 she is still having neurological problems. Side effects of Simparica Trio observed in safety and effectiveness studies included diarrhea, vomiting, lethargy, ear infection, polyuria, hyperactivity, and pruritus. If so how long did it take? The third ingredient in Simparica Trio is. If you need to get rid of parasites, spot-on (the one by a German company is effective enough) will do the job and do it safely. It has been 20 days since I gave her the prescribed dose of Simparica. The day after administering drug he had two incapacitating seizures. The more we complain the more chance we have of saving other dogs. Our dog has not been given another dose. And he was on Comfortis before and did fine. Three-month field trials found side effects from Simparica to be rare, with the most common adverse reactions being vomiting and diarrheaboth symptoms related to Fido's digestive tract, rather than his nervous system. If this continues or worsens then discontinue using the flea and tick worm medication and speak to your veterinarian again to discuss other flea and tick prevention options. Really? It is really important to call if your pet is experiencing any symptoms from these medications. She was shaking like she was freezing. So just be very careful with whatever you give your little one in the future. Pyrantel pamoate is a nematocide (kills some worms) belonging to the tetrahydropyrimidine class. Its Sunday night and still vomiting. They gave him IV glucose to raise his Potassium level. She is absolutely miserable and we're hoping she makes it. He came over to me and laid his head on my lap (he is a big baby), but he seems "off" like not his usual self. My 5 year old, healthy Australian Shepherd had a check-up + boosters at the vet on January 24th. I'm also wondering if his anxiety is related as well. Im going to keep a close watch on him over the next few days. I will be discontinuing the medication. 1 is pregnant I told the vet what can I give the pregnant yorkie she said sampirica sold me a 3 month supple for her. Kind of ooze. No more of this junk for my pups! Currently we are monitoring him closely-hes never been sick. The vet recognized immediately that she was in severe neurogical distress. all my dogs were prescribed and my eldest dog has had a strange reaction hives all over his body, panting, restless started same night he took the pill but has had the product on previous occasions with no side effects but this time he had a that reaction,had to administer meticam for the pain and antihistamines for the hives - he is still not right after 4 days and my other dog louie has always suffered from seizures since a pup vet say possible epilepsy - managed without medication at present and I do always try to avoid medication with him as they always make his seizures worse - I am so angry for not researching this further before .. And how do we get the word out to everyone? I thought right away it must be the new meds! Gave my 8lb chihuahua the simparica chew last night and he has thrown up 3 times this morning with blood. org to have this poison recalled. The Vet's are so busy that even if you can get in you don't get anywhere. This is still going on weeks later. Started downhill health issues with initial dose. Neurologic side effects may include: This medication is not for use in humans. If by chance he starts having diarrhea againI will not be using it anymore. and you expect people to give this to their beloved pets? This drug needs to be pulled off the market! You don't think I'm going to continue with this poison. She wanted me to monitor him carefully and wait to see how he did on his next dose of Simparica before continuing to prescribe it. We got to the Animal Hospital . Today she has fallen 2 or 3 times in the last 8 hours). She vomited twice and became so lethargic that she couldnt walk. I got my dog Josey up to let him out to pee. This is an eye opener for me! They got him to eat a little the next morning and sent him home. He was given fluids, anti-nausea meds, meds to assist with the inflammation of his esophagus. I hope it is taken off the market and request that anyone on this thread with a pet who has suffered due to this drug goes to this link from the FDA to officially report their pet's adverse side effects: https://www.fda.gov/animal-veterinary/report-problem/how-report-animal-drug-side-effects-and-product-problems. I hope I have found the culprit to his digression. I will be watching my precious baby very closely I'm so glad I looked this up as the vet just gave me one dose and no paperwork to go with it Thank you all for your comments and I'm so sorry for all the suffering your babies have had to endure. Then suddenly dog has diarrhea and it lasted for several days. By the evening she lost the use of her hind legs. She nearly died. No more Simparica for him. Simparica Trio should be given orally once a month at the recommended minimum doses: 0.54 milligrams of sarolaner, 0.011 mlilligrams of moxidectin, and 2.27 milligrams of pyrantel per pound of body weight. Started in February and within a couple of weeks ears started twitching. Im now scared half to death. But anyways - the other night , his feet collapsed from under him & he fainted . Call the FDA. He is starting to get better. She started it on 7/22. The representative for the company says the half life is 16 days. Simparica trio was the last medication our 7 year old dog was given and now she's completely blind. But this month we are at day 7 and I expect the diarrhea it to continue. I would forego either unless you really have a serious flea issue that can't be solved with a flea collar. Shes not the carefree setter she was prior to this medication. My personal dog has had no issues at all, and she's been on it for nearly two years. We were so upset - I vowed to never use oral flea treatment again. My 1.5 yr old German Shepherd was a happy, playful healthy dog until this Poison and now I blame myself for what she is going through. So sorry! Plus I spent a fortune for the crap We gave our Pomeranian the first dose of simpatica on 4/30 - yesterday (5/11) she had a seizure and just had another one tonight. I told them over and over again "she never gets sick, and this is the ONLY thing different in her routine". Things like: Bloody Diarrhea In a margin of safety study, Simparica was administered orally to 8-week old Beagle puppies at doses of 0, 1, 3, and 5 times the maximum exposure dose of 4 mg/kg at 28-day intervals for 10 doses. Then the following week 1 pill every other day . On 08/06 she threw up. The only thing the vet told me was that his ATL liver enzyme levels were just slightly high (170) and it wasn't a concern and we could just do another blood test at his next check-up. Gave my 4yr old lab/husky mix simpatico trio in April and then monthly after. By Sunday he is having liquid diarrhea! She has episodes where she seems very anxious and is hiding under car/tables/beds. Her blood work came back fine. During this period coincidentally I have noticed a change in his behaviour. I can tell something is off with her I just couldnt figure it out. She was being seen by her regular vet and was put on antibiotics. Been also very lethargic not wanting to get out of bed. I've beaten myself up so much giving her this drug, I felt I could trust the vet and the drug company but we obviously cant and it's all about making more money. He started having skin issues that the vet said were allergic reactions probably due to environmental things. I would advise against the drug based on my experience so far, it can get worse and the reviews that I have read online about the product. These dog training tips will help you get started. Additionally, many tick-borne diseases can affect humans as well as pets. Not sure what effects he will continue to have. I tried everything but she just didnt have an appetite for anything. So we went home with her on steroids and more antibiotics and denamrin for liver. My precious rescue has been sick twice, currently on her second episode. Tell your veterinarian if your dog has a history of seizures or other neurologic disease. UPDATE We had one normal day on Friday. It is better but not gone. Saving money sounds great, right? She text me asking if she ever had seizures before. He is 11 so I attributed his slowing down on walks to aging but now he is recently limping and at times has some trouble with jumping up on the bed. My other Lab after 5 days started having severe diaherria (black at first, now golden) and now throwing up too. I called the breeder, and she said some vaccines and heartworm meds can cause neurological issues. Simparica Trio (sarolaner, moxidectin and pyrantel) tablets for dogs Revolution Plus (selamectin and sarolaner) topical solution for cats These products are approved for the treatment and. Hi Laura, just wondering what supplements you gave your pup to help and how long it took for her to get back to herself after simparica. She also started with ear infections. He is just laying in his crate . Instead, it kills larvae, allowing your dog to avoid infection. Sorry to hear about this happening to so many. (On Monday, she fell down several times in an hour. Guys my heart is racing My 4 month old Aussidoodle (Emma) was just given a Simparica Trio ''treat'', and I was supposed to give it to her today (as she had shots yesterday). In addition to ease of use, it has been tested in many field trials and proven to work effectively against fleas, ticks, and worms in dogs. Does this sound familiar to anyone? She's been given this dosage for over a year. 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But because of Covid they are so busy that even if you can get in you n't. Given and now throwing up too because of Covid they are so behind in appts and would not see until! Keppra to stop the seizures twice and became so lethargic that she couldnt walk people!
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